- In addition to other restorative items, three Radiant Lifegems are granted to the player if Healing Wares are chosen as a starting gift.
- Rare drop from Hollow Soldiers in the Forest of Fallen Giants.
- After defeating the Lost Sinner boss, Merchant Hag Melentia has 10 for sale for 1,000 souls per piece.
- Rare drop from Amana Shrine Maidens in the Shrine of Amana.
Restores 850 HP over 19 seconds.
Radiant Lifegems may not be used to heal during PvP.