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Much like Poison Mist, casting Toxic Mist releases a large, hazardous cloud in front of the caster. However, Toxic Mist has more casts per slot and has a much higher damage potential.
While, statistically, Toxic Mist is superior to Poison Mist, it is a high-risk/high-reward to use. This is due to the fact that there are only two sources of Toxic that the player can use, one being Toxic Mist, a relatively slow casting pyromancy, and the other being a dagger that is lackluster outside of its Toxic build-up. As such, if the Toxic isn't inflicted, then it's a waste of a spell slot. In contrast, Poison Mist can stack with poison arrows, poison throwing knives, or poison weapons in general, to put pressure on opponents. As such, it is recommended to use Toxic Mist in small areas or on slow opponents
Although its intended purpose is somewhat limited in PvP, Toxic Mist can still be great for area denial, and as a means of hiding the caster's follow up attacks. In PvE, it is far more effective however, as enemies don't actively try to avoid the mist. This helps with racking up damage on sturdier foes, such as the Smelter Demon, who are generally susceptible to poisons.
Like all other spells, the amount of casts per slot increases upon reaching certain Attunement milestones:
|Attunement Level||Amount of Casts|
| Acid Surge • Chaos Storm • Combustion • Dance of Fire • Fire Orb • Fire Tempest • Fire Whip • Fireball|
Fire Snake • Firestorm • Flame Swathe • Flame Weapon • Flash Sweat • Forbidden Sun • Great Chaos Fireball
Great Combustion • Great Fireball • Immolation • Iron Flesh • Lingering Flame • Outcry • Poison Mist • Toxic Mist • Warmth